Corinne’s work on understanding the effects of Neanderthal haplotypes in modern humans using data from the eMERGE network was featured in a Nature News article: Neanderthals had outsize effect on human biology
We are very grateful to the Vanderbilt Center for Quantitative Sciences for funding our pilot project. Working together with Bennett Landman’s group, we will build a pipeline for integrating phenotypes extracted from medical images and genetic information from Vanderbilt’s BioVU database. This will enable us to test the effects of many evolutionarily and clinically relevant mutations on a wide range of human phenotypes.
Congratulations to Alex for winning the Best Research Presentation Award at the recent Gordon Human Genetics and Genomics Conference! Her presentation, “Are Genetic Interactions Influencing Gene Expression Evidence for Biological Epistasis or Statistical Artifacts?”, is the culmination of her hard work to evaluate the conflicting evidence for and against epistatic gene regulatory interactions in humans.
If you are interested, check out the bioRxiv preprint:
Are Genetic Interactions Influencing Gene Expression Evidence for Biological Epistasis or Statistical Artifacts?